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Any adjournment of the trial date would increase those costs significantly, and any semblance of proportionality would then be lost. Mr Justice Coulson accepted amendments agreed by the parties but rejected two amendments relating to disputed claims 8211; one in respect of a car park smoke ventilation system, the other alleged defects in the roofs. Besford: no CFA to transfer.

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Lifestyle intervention Nicotinic acid or fibrates (gemfibrozil, fenofibrate) Lifestyle intervention Glycemic control Fibric acid derivatives, niacin, high-dose statins (in patients with elevated LDL-C) First improve glycemic control and use a high-dose statin Second choice: improved glycemic control plus statin plus fibric acid derivative b Third choice: Improved glycemic control plus statin plus nicotinic acid. a Patients with triglyceride levels gt;400 mgdL may require insulin in addition to monotherapy or combination therapy lipid-lowering agents. b bGemfibrozil causes a two- to sixfold increase in statin area under the curve and increases the exposure to many recently approved drugs for the treatment of diabetes. Alternatively, fenofibrate does not adversely affect either the metabolism or the pharmacokinetics of the statins studied.

Support is often provided by charities - indeed the group that helped Keith, Oldham TRANX, was founded by Barry Haslam, an accountant who suffered long-term brain damage due to benzodiazepine addiction. Barry was prescribed ativan, librium and Valium for ten years, after suffering anxiety trying to juggle two jobs alongside accountancy exams. He claims they wiped his memory and left him with brain shrinkage, visible on a scan. 'Benzodiazepines turned me into an angry man. I had felt calmer initially but those effects quickly wore off. 'One Christmas I nearly hit my wife and put my fist in the wall instead.

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